Allertol, The Allergy Drop Solution

Allerto The Allergy Drop SolutionAllergy Drops, Not Shots: Simple....ALLERTOL® 


Allertol FAQS

Who was the originator of ALLERTOL?
Dr. John Shea

A Texas native who grew up in Fort Worth, Dr. Shea attended Paschal High School, Tarrant County College, and then University of Texas at Arlington, where he graduated with a Bachelor of Science degree.   He then attended the University of Texas Medical Branch in Galveston where he finished medical school in 3 years, completed 2 years of general surgery, and 3 years of otolaryngology / head and neck surgery residency.  In 1979 became certified by the American Board of Otolaryngology / Head and Neck Surgery after scoring in the top 10 out of 500 on this national board exam.  That same year, he started practicing Otolaryngology in Fort Worth. In 1987 he sat for written and oral exams and became a Fellow of the American Board of Otolaryngic Allergy.

Personal experience with allergies began with chronic food allergies during infancy, resulting in sinus and middle ear infections. "Hayfever" began in early teens.  Then during adult years, multiple chronic food allergies:  migraines from pork, gastrointestinal problems from onion, heart irregularities from processed soy, tinnitus from chocolate, etc. 

Treatment has ranged from antihistamines, decongestants, steroid sprays, to a series of allergy shots from the Otolaryngology Clinic in Galveston.   Eventually, sinus surgery was performed, but continued chronic delayed food allergy problems continued.  Persistent nasal congestion and eventually sinus infections returned.  Changing the diet was difficult and helped little.  Finally, the solution was found:  the ALLERTOL METHOD of sublingual testing and treatment of common foods resulted in resolution of nasal congestion, migraines, GI upset and an irregular pulse:  bigeminy.

ALLERTOL® was born. 

Patents for the method of testing and treating delayed food allergies were awarded in 2014 and 2018.

What is an allergy?

An allergy is a immune system disorder characterized by abnormal reaction to a substance that is not expected in the average person. The concept of allergy was first introduced and defined in 1906, by a pediatrician from Vienna named von Pirquet, describing abnormal reactions to food, pollen and dust.

Why did I develop allergies?

The tendency to develop an allergy may have to do with genetics and to repeated exposure to a food or airborne substance. This can allow dander, dust mite and pollen to induce an allergic response from your immune system. Research has implicated a malfunctioning FOXP3 gene, that can affect T cells. These cells can induce tolerance to foreign protein substances that are eaten or inhaled.  Certain regulatory T cells appear to be important in preventing damage from inflammation. They can send messages to the immune system to allow safe passage of foreign proteins. It is hoped that further research can produce more functional Treg cells and thus a more tolerant immune system for the allergy sufferer.

What areas are affected, and what symptoms can occur from allergies?

An allergy can involve any part of the body involving any of 10 body systems, especially delayed T cell mediated immune reactions. Most common systems affected include respiratory, digestive, vascular, nervous and integumentary (skin).  Symptoms from airborne allergies mostly are respiratory such as nasal congestion, cough and asthma.  Symptoms from delayed food allergies tend to affect several systems, producing chronic nasal congestion, GI problems, headache, inner ear, and skin itching / eczema / rashes.

Airborne allergies tend to be more of a problem when the patient is up and about; may worsen seasonally, outdoors.

Delayed food allergies tend to be perennial, do not worsen outdoors, and tend to be a common cause for chronic perennial dependent rhinitis:  nasal blockage that worsens supine, may rotate from side to side, and is a major cause for restless sleep, snoring, dry mouth and fatigue.  

In addition to nighttime nasal blockage, other symptoms may include persistent runny nose, repeated sneezing, itching of the ears / nose / eyes, throat clearing, common headache, migraine headache, sinus infections, middle ear problems, skin itching, hives, eczema, cough, wheezing, fatigue and trouble concentrating.

Delayed food allergy can cause nasal polyps and allergic 'shiners'.

Some cases of fluctuating hearing loss, dizziness and / or buzzing in the ear (Menieres) have been associated with delayed food allergies.

How do sublingual drops work?

Special giant cells of the mouth, called “dendritic cells” discovered by the German pathologist Paul Langerhans, take up protein molecules present in the drop solution.  These Langerhans giant cells then deliver Tiny bits of these proteins to T cells, which then send messages to the immune system to induce tolerance to these proteins. These specialized T cells induce “down regulation” of the immune system, decreasing inflammation of any of the body systems.

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Is Sublingual Immunotherapy FDA approved?

Yes, the FDA has approved SLIT (sublingual immunotherapy) in the form of tablets for weeds tree and grass allergies.  The FDA has approved the extracts used in sublingual immunotherapy many years ago, for skin testing and allergy shots. The FDA permits the medical practitioner to offer allergy drops "off-label" when it is in the best interest of the patient to do so.  The safety and convenience of allergy drops is definitely in the patients best interest.

Are other FDA approved products being used “off label” by doctors?

Yes. The cosmetic use of Botox is an example. Botox was originally approved by the FDA for treatment of muscle spasm. But its “off label” cosmetic use for treating facial wrinkles was commonplace, prior to its final approval by the FDA on April 15, 2002.

Does everyone get the same thing in the vial?

No. Each individual receives specific treatment depending upon history and clinical evaluation. In the case of the airborne allergy vial, results from skin testing are used to determine safe starting doses of the various pollens, molds, animal danders, dust mite, etc.

In the case of the delayed food allergies, a detailed history and sublingual evaluation is done to determine which group of food proteins are used.

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Can the allergy drop solution be used to treat sudden severe reactions (anaphylaxis) to a single known offending food, such as severe reactions to peanut and fish?

No. Allergy drops are not used for anaphylactic reactions to foods, just as shots are not normally recommended for this problem. Allergy drops food protein groups are not provided if are there is a history of severe, sudden anaphylactic reaction to a specific food producing hives, life-threatening asthma, and/or swelling of a part of the body, such as swelling of the mouth, tongue, or throat.  The patient with a history of a sudden reaction to a known food, must strictly avoid that food, and be prepared to discover these reactions early so prompt medical attention can be delivered. It may be helpful to join one of the online food allergy networks. It is very important to inform the health care provider if there is a history of sudden severe food reaction, or if such reactions develop in the future, and keep up with management guidelines.

What can I expect the allergy drops to do?

Allergy drops of common groups of food can uncover the cause for multiple chronic problems and provide a safe and effective long lasting solution.   Allergy drops of airborne allergens can be an effective solution as well. 

What alternatives do I have to treating my allergies?

You can avoid some allergens, medicate to reduce symptoms or treat the immune system. Avoidance - some allergens such as grass can be avoided by giving the lawn mowing job to someone else. Avoiding common foods such as corn can be challenging, as corn is pervasive in our diet.

Medication – steroid nasal sprays, antihistamines and anti-leukotrienes can used prior to airborne allergen exposure. Medications have had a limited effect upon delayed food reactions.

Immunotherapy – allergy shots and allergy drops for airborne allergies have been very effective for treating seasonal symptoms..  Allergy drops for delayed food allergies has been very effective for treating multiple body system symptoms and problems.

Is it really necessary for me to avoid things to which I am allergic?

Treating delayed food allergies with the ALLERTOL®  method, elimination diets are not necessary. 

Airborne allergens are avoided as possible, especially animal dander and grass pollen, especially with asthma.

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When can I stop taking medications that I have been using to treat allergy problems?

As symptoms are relieved, you may taper off of these medications.

How long should I expect to receive the allergy drops before I am “cured”.

There is no "cure" for allergies at this time.  Sublingual immunotherapy requires up to 5 years for relief of allergy symptoms.  When symptoms are controlled, the drops are tapered from 3 / day --> 2 / day, then eventually 1 / day before immunotherapy completed.

I have been told that I have “vasomotor rhinitis”. Decongestant medications and surgery to open the nasal airways have been recommended. Could chronic food allergies be the problem?

Yes. As stated in the text “Otolaryngic Allergy”, regarding patients diagnosed with vasomotor rhinitis, “Attention should be directed toward delayed-onset food allergy…”  Most delayed food allergy reactions are associated with Type IV cellular immune reactions.

How long will it take before I can notice some relief of my allergy symptoms?

Symptoms from delayed food allergies may begin to be relieved as soon as the first few days of sublingual allergy drop testing.

Airborne allergy symptoms may be reduced within a few months of starting sublingual immunotherapy.

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Does it matter if I eat around the same time I use the drops?

Yes.  The giant cells of the mouth should be “starved” by avoiding chewing gum, mints, drinks, or having other food prior to placing the allergy drop under the tongue.

Besides molecules of food or airborne antigens, and sterile water, what else is in the allergy drop vial?

Pure glycerin from a plant source, as a preservative.

Can glycerin preservative in the allergy drop solution cause a problem?

Yes.  Some people are sensitive to glycerin, which is a common ingredient in most toothpaste, soaps and lotions. Commercially made glycerin can come from animal (beef or pork) and / or vegetable sources. The glycerin used in the allergy drop solution is derived totally from plant sources, made here in the good old USA.  If you know you react to glycerin-containing products, you may not be able to receive allergy drops. However, a weak allergy drop solution of glycerin can sometimes be used to treat glycerin reactions.

Have there been fatal reactions reported from using allergy drops or shots?

In 2007, a 15 year literature review reported by Dr. Leatherman from Southwestern Medical School in Dallas, there have been no life-threatening reactions reported with allergy drops. Millions of allergy drops have been given safely to thousands of patients.

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What are the reactions to delayed food allergy drops?

The reactions to delayed food allergy drop testing can be temporary headache, diarrhea, nasal symptoms, snoring and restless sleep. skin itching  and rash, cough and throat clearing.  By far, the most common reaction is multi-symptom relief !

How is a reaction to the allergy drop treated?

The allergy drop use is temporarily stopped.  Benadryl or long acting antihistamine may be taken. After seekikng healthcare provider recommendations, a weaker allergy drop may be used.   

What could prevent use of the drops?

If there is a history of severe allergic reaction requiring emergency treatment, or unstable medical illness / asthma, sublingual immunotherapy may be precluded.

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How often are the follow-up visits?

At least annually; more often as indicated.

How do I reorder the drops?

Contact the office.  Your vials will be ready within a week.  If a trip is planned, order vials early.

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What is concomitant food allergy?

Certain foods, when eaten during your allergy season, can make your allergies worse.

  Concomitant Foods
Elm milk, mint
Ragweed milk, mint, melons, banana
Marsh Elder wheat
Pigweed pork, black pepper
Posion Ivy/Oak/Sumac pork, black pepper
Cedar beef, yeast
Grass apple, carrot, celery, potato
Oak egg, apple
Cottonwood lettuce
Pecan corn, banana
Mesquite cane sugar, orange
Molds cheese, mushrooms, candida, ground molds
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Allertol is NOT used to prevent or treat immediate life-threatening allergy/anaphylaxis.

Contact an Allertol Provider
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Allertol is NOT used to prevent or treat immediate life-threatening allergy/anaphylaxis.

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